June 27, 2025 at 8:00 pm – 10:00 pm (EST)

Neurophysiological Basis of Complex Regional Pain Syndrome

Presented by: Shrikant J. Chinchalkar, MTh.O, B.Sc.OT, OTR, CHT

Webinar Description:

Complex Regional Pain Syndrome (CRPS), historically referred to by various names including reflex sympathetic dystrophy, causalgia, “red hand disease,” and Sudeck’s atrophy, is a challenging neuropathic pain disorder that typically arises following trauma or surgery. It is characterized by pain disproportionate to the inciting event and is frequently accompanied by sensory, autonomic, and motor disturbances. In 1993, the International Association for the Study of Pain (IASP) introduced the term CRPS, with formal diagnostic criteria established in 1994.
CRPS was classified into three categories: Type I (without a definable nerve lesion), Type II (with an identifiable nerve lesion), and Type III (not otherwise specified). The pathophysiology of CRPS involves a destructive yet progressive cycle that traverses acute, dystrophic, and atrophic stages. These evolving changes affect peripheral tissues and induce maladaptive cortical plasticity, contributing to the complex emotional and functional impairments seen in affected individuals. This presentation explores the neurophysiological mechanisms underlying CRPS and proposes a symptom-based framework to guide clinical management and improve patient outcomes in this often-debilitating condition.

Learning Objective

• Upon completion of this presentation, participants will be able to:
• Describe the neurophysiological mechanisms underlying the development and progression of Complex Regional Pain Syndrome (CRPS).
• Understand the mechanism of joint stiffness and progression.
• Understand the neurophysiology of CRPS
• Apply a symptom-based, physiological, and mechanical framework to formulate individualized management strategies for patients with CRPS.

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